NOTE: The Stanley Qi Lab has moved to Stanford. The new lab website is http://qilab.stanford.edu.
The epigenetic regulation of gene expression plays a crucial role for cell development and differentiation, with aberrations causing complex diseases. Novel technology that enables functional understanding of mammalian genomes brings great opportunities for the systematic identification of genetic and epigenetic programs underlying development and disease. The Qi lab is actively developing and applying new genome engineering technologies to study mammalian genomics, and seeking new ways to direct cell fate reprogramming and decision making. Our long-term goal is to leverage genome and epigenome engineering as new avenues for understanding of genotype-disease relationship and for developing gene- or cell-based therapeutics.
We are part of the UCSF Center for Systems and Synthetic Biology and UCSF Cellular and Molecular Pharmacology. UCSF Center for Systems and Synthetic Biology is one of the NIH-NIGMS funded national centers for Systems Biology, which serves as a nucleus at UCSF for interdisciplinary and quantitative explorations into how biological systems function.